To that end, we’ve put together a tier list to help you decide which one to pick for your next game. While most leaders can competently pursue any of these conditions, not are created equal. Each civ and leader favors at least one of the four different paths to victory (domination, science, diplomacy, and culture). With over 40 different civilizations to play, Civ 5 is a massively replayable 4X strategy experience.